Antifungal activity of natural products indicated by herb sellers (raizeiros) for the treatment of oral candidiasis

Authors

  • Vanessa Maria Freire Abílio Universidade Estadual da Paraíba/ UEPB
  • Bruno da Silva Mesquita Centro Universitário de João Pessoa- UNIPE
  • Evelyn Darly da Silva Centro Universitário de João Pessoa- UNIPE
  • Fabíola Vilar de Queiroz Carvalho Centro Universitário de João Pessoa- UNIPE
  • Luciana Lucena Aranha de Macêdo Departamento de Ciências Farmacêutica do Centro de Ciências da Saúde da Universidade Federal da Paraíba/UFPB
  • Ricardo Dias de Castro Departamento de Clínica e Odontologia Social do Centro de Ciências da Saúde da Universidade Federal da Paraíba/UFPB

Keywords:

oral candidiasis, Schinus terebinthifolius, Cinnamomum zeylanicum, Punica granatum.

Abstract

An increasing resistance of Candida yeasts to the synthetic antifungals currently available has driven the search for new plant-derived antifungal compounds. In this respect, the present study aimed to evaluate the in vitro antifungal activity of decoctions from Schinus terebinthifolius Raddi (Brazilian pepper tree), Cinnamomum zeylanicum Breym (cinnamon) and Punica granatum Linn (pomegranate) against three species of Candida genus (C. albicans, C. tropicalis and C. krusei). Such plant material was sold by herb sellers in three distinct street fairs (A, B and C). The test to determine the products antifungal activity was performed in triplicate by means of the diffusion method on solid medium, in which sterile filter paper discs were soaked in 50 µL of the extracts and then placed on culture medium. Data were assessed by measuring the diameters of halos of fungal growth inhibition, in millimeters (mm), and it was considered the mode of the values found. Antifungal activity of S. terebinthifolius Raddi and C. zeylanicum Breym was observed against C. krusei, but were identified differences among the products obtained in different locations. Punica granatum Linn decoction presented antifungal activity on the three yeasts under study. Also, were found differences among the products acquired in the street fairs, but only the samples of Punica granatum Linn from fair A were able to inhibit fungal growth of all yeasts analyzed. Thus, it is concluded that all the products assessed showed antifungal activity, but differences were found depending on the location where these were obtained and on the sensitivity to the strains assayed.

Downloads

Download data is not yet available.

Author Biographies

Vanessa Maria Freire Abílio, Universidade Estadual da Paraíba/ UEPB

do mestrado do Programa de Pós-Graduação em Odontologia pela Universidade Estadual da Paraíba/ UEPB

Bruno da Silva Mesquita, Centro Universitário de João Pessoa- UNIPE

Estudante do curso de graduação em Odontologia do Centro Universitário de João Pessoa- UNIPE

Evelyn Darly da Silva, Centro Universitário de João Pessoa- UNIPE

Estudante do curso de graduação em Odontologia do Centro Universitário de João Pessoa- UNIPE

Fabíola Vilar de Queiroz Carvalho, Centro Universitário de João Pessoa- UNIPE

Estudante do curso de graduação em Odontologia do Centro Universitário de João Pessoa- UNIPE

Luciana Lucena Aranha de Macêdo, Departamento de Ciências Farmacêutica do Centro de Ciências da Saúde da Universidade Federal da Paraíba/UFPB

Professora Adjunta do Departamento de Ciências Farmacêutica do Centro de Ciências da Saúde da Universidade Federal da Paraíba/UFPB

 

Ricardo Dias de Castro, Departamento de Clínica e Odontologia Social do Centro de Ciências da Saúde da Universidade Federal da Paraíba/UFPB

Professor Adjunto do Departamento de Clínica e Odontologia Social do Centro de Ciências da Saúde da Universidade Federal da Paraíba/UFPB

Downloads

Published

2014-11-26

How to Cite

1.
Abílio VMF, Mesquita B da S, da Silva ED, Carvalho FV de Q, de Macêdo LLA, de Castro RD. Antifungal activity of natural products indicated by herb sellers (raizeiros) for the treatment of oral candidiasis. Rev Cubana Estomatol [Internet]. 2014 Nov. 26 [cited 2025 Feb. 7];51(3):8-13. Available from: https://revestomatologia.sld.cu/index.php/est/article/view/34

Issue

Vol. 51 No. 3 (2014): JUL- SEP

Section

Research Article

License

Authors retain all rights to their works, which they can reproduce and distribute as long as they cite the primary source of publication.

The Rev Cubana Estomatol is subject to the Creative Commons Attribution-Non-Commercial 4.0 International License (CC BY-NC 4.0) and follows the publication model of SciELO Publishing Schema (SciELO PS) for publication in XML format.

You are free to:

  • Share — copy and redistribute the material in any medium or format.
  • Adapt — remix, transform, and build upon the material.

The licensor cannot revoke these freedoms as long as you follow the license terms.

Under the following terms:

No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.

Notices:

  • You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation.
  • No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.

 

 

 

 

 

 

 

Most read articles by the same author(s)