Antifungal effect of tinctures from propolis and pomegranate against species of Candida

Authors

  • Leopoldina Fátima de Dantas de Almeida Universidade Federal da Paraíba
  • Bachiller Yuri Wanderley Cavalcanti Universidade Federal da Paraíba
  • Bachiller Ronaldo Lira Júnior Universidade Federal da Paraíba
  • Edeltrudes de Oliveira Lima Universidade Federal da Paraíba
  • Ricardo Dias de Castro Universidade Federal da Paraíba

Keywords:

Candida albicansM Apis mellifera, Punica granatum.

Abstract

The use of natural products in Dentistry has been shown as an alternative source
against oral diseases, including fungi infections, generally caused by Candida spp.
The aim was to evaluate the antifungal action of tinctures from propolis (Apis
milifera) and from pomegranate (Punica granatum) on Candida albicans (ATCC
76618), Candida krusei (ATCC 6538) and Candida tropicalis (ATCC 13803). The
antifungal activity of tinctures was evaluated by Minimum Inhibitory Concentration
method on Saburaud Dextrose Agar (Difco®). Six wells were confectioned, with 6 mm
of diameter, to the insertion of 50 µL of tinctures. Six serial concentrations were
evaluated, been 200 mg/mL the initial concentration for tincture from propolis and
300 mg/mL the initial concentration for tincture from pomegranate. Later, the Petri
plates were incubated in bacteriological incubator for 48 h on 37 ºC. Data analysis
for Minimum Inhibitory Concentration was conducted by measurement of inhibition
zones, been considered inhibited when equal or bigger than 10 mm of diameter. For
tincture from pomegranate, was verified that the Minimum Inhibitory Concentration
on Candida albicans, Candida krusei and Candida tropicalis were 9.37 mg/mL,
9.37 mg/mL and 18.75 mg/mL, respectively. For tinctures from propolis, the
antifungal action was verified only in pure concentration on Candida krusei and Candida tropicalis, but it was not observed on Candida albicans. The tinctures from
pomegranate and propolis had antifungal activity on evaluated strains, except for
tincture from propolis on Candida albicans.

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Published

2012-04-20

How to Cite

1.
de Dantas de Almeida LF, Wanderley Cavalcanti BY, Lira Júnior BR, de Oliveira Lima E, Dias de Castro R. Antifungal effect of tinctures from propolis and pomegranate against species of Candida. Rev Cubana Estomatol [Internet]. 2012 Apr. 20 [cited 2025 Feb. 21];49(2):99-106. Available from: https://revestomatologia.sld.cu/index.php/est/article/view/2755

Issue

Vol. 49 No. 2 (2012): APR- JUN

Section

Research Article

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