Factors related to the occurrence and classification of radiation-induced oral mucositis

Authors

  • Tatiana Stuart Vieira Holmes Universidade Estadual da Paraíba (UEPB)
  • Manuela Gouvêa Campêlo dos Santos Universidade Estadual da Paraíba (UEPB)
  • Danubia Roberta de Medeiros Nóbrega Universidade Estadual da Paraíba (UEPB)
  • Jozinete Vieira Pereira Universidade Estadual da Paraíba (UEPB)
  • Daliana Queiroga de Castro Gomes Universidade Estadual da Paraíba (UEPB)
  • Maria do Socorro Vieira Pereira Universidade Federal da Paraíba (UFPB)

Abstract

Introduction: oral mucositis is considered the most common acute complication resulting from head and neck antineoplastic therapy. It is characterized by erythema and mucosa edema, commonly followed by ulceration and peeling.
Objective: this study aimed to assess the factors related to the onset and grading of oral mucositis in patients undergoing radiotherapy for head and neck cancer.
Methods: a longitudinal study was conducted, comprising 22 patients with a diagnosis of head and neck malignancy undergoing radiotherapy. These patients were evaluated during 4 weeks and they were checked for the onset and grading of oral mucositis during antineoplastic treatment.
Results: according to coefficient ñ tests by Spearman, U Mann-Whitney and Kruskal-Wallis, oral mucositis developed in 95.45% of patients who underwent head and neck radiotherapy, with higher grading among smokers compared with those of non-smokers, with statistically significant difference (p = 0.034).
Conclusion: these results suggest that there was no association between age, alcohol consumption and patients' oral hygiene with the onset and grading of mucositis. Smokers were found to show higher grading of radiation-induced oral mucositis on its onset.

Keywords: head and neck cancer, oral mucositis, radiotherapy.

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Published

2014-05-15

How to Cite

1.
Vieira Holmes TS, Campêlo dos Santos MG, de Medeiros Nóbrega DR, Vieira Pereira J, de Castro Gomes DQ, Vieira Pereira M do S. Factors related to the occurrence and classification of radiation-induced oral mucositis. Rev Cubana Estomatol [Internet]. 2014 May 15 [cited 2025 Mar. 14];51(1):45-51. Available from: https://revestomatologia.sld.cu/index.php/est/article/view/157

Issue

Vol. 51 No. 1 (2014): JAN- MAR

Section

Research Article

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