Aesthetic results in post-surgical nasal defects regenerated with autologous platelet- and leukocyte-rich fibrin

Authors

Keywords:

nasal surgical procedures, autologous fibrin rich in platelets and leukocytes, regenerative medicine, targeted tissue regeneration.

Abstract

Introduction: In the reconstruction of nasal skin defects, several techniques have been used worldwide. Innovative practices use platelet concentrates for their modulating properties and favoring tissue regeneration.

Objective: Determine the aesthetic results associated with the use of autologous fibrin rich in platelets and leukocytes, for the regeneration of post-surgical nasal skin defects.

Methods: A quasi-experimental, longitudinal and prospective study was conducted in the Maxillofacial Surgery Service of “Arnaldo Milián Castro” University Hospital in the city of Santa Clara, Villa Clara province, Cuba, from September 2015 to June 2019. An intentional, non-probabilistic sampling of 31 patients was carried out. From a blood donation from the patient, a fibrin membrane rich in platelets and leukocytes was obtained, which was sutured in the post-surgical nasal defect. Variables such as the aesthetic result were studied, evaluated on the basis of parameters such as elasticity, color, volume and surface.

Results: The mean age was 62.71 ± 11.09 years and 61.29% of the sample corresponded to the male sex. A good aesthetic result was shown by 90.32% of the patients, which was significantly associated with the degree of epithelialization.

Conclusions: A good aesthetic result was obtained in patients where the fibrin membrane rich in leukocytes and autologous platelets was used, regardless of the presence of diabetes mellitus and toxic habits. The aesthetic result was significantly associated with the degree of epithelialization and age.

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Author Biographies

Leodanyi Adán Socarrás, Hospital Oncológico Universitario “Dr. Celestino Hernández Robau”, Servicio de Cirugía Oncológica de Cabeza y Cuello. Santa Clara, Villa Clara, Cuba.

Especialista en Cirugía Maxilofacial del servicio de Cirugía de Cabeza y Cuello de Villa Clara.

Tairí Borges García, Universidad de Ciencias Médicas de Villa Clara, Facultad de Estomatología. Santa Clara, Villa Clara, Cuba.

Especialista en Cirugía Maxilofacial

Manuel Antonio Arce González, Universidad de Ciencias Médicas de Villa Clara, Unidad de Investigaciones Biomédicas. Santa Clara, Villa Clara, Cuba.

Especialista en Medicina Interna y Hematología

Alba María Díaz Suárez, Universidad de Ciencias Médicas de Villa Clara, Unidad de Investigaciones Biomédicas. Santa Clara, Villa Clara, Cuba.

Licenciada en laboratorio clínico

Carmen Rosa Cantero Marín, Universidad de Ciencias Médicas de Villa Clara, Unidad de Investigaciones Biomédicas. Santa Clara, Villa Clara, Cuba.

Licenciada en laboratorio clínico

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Published

2022-01-31

How to Cite

1.
Adán Socarrás L, Borges García T, Arce González MA, Díaz Suárez AM, Cantero Marín CR. Aesthetic results in post-surgical nasal defects regenerated with autologous platelet- and leukocyte-rich fibrin. Rev Cubana Estomatol [Internet]. 2022 Jan. 31 [cited 2025 May 17];59(4):e3835. Available from: https://revestomatologia.sld.cu/index.php/est/article/view/3835

Issue

Vol. 59 No. 4 (2022): OCT- DEC

Section

Research Article

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