Mandibular replacement with a customized titanium prosthesis after ameloblastoma excision
Keywords:
odontogenic neoplasms, ameloblastoma, mandibular reconstruction, titanium prosthesis.Abstract
Introduction: Ameloblastoma is a benign tumor of odontogenic epithelium with a tendency to local recurrence if not removed appropriately. Reconstruction alternatives include the use of microvascularized free flaps, plates and customized titanium prostheses.
Objective: Describe a case of mandibular replacement with a customized titanium prosthesis after ameloblastoma excision.
Case presentation: A case is presented of a female 44-year-old patient who presented a radiographic finding during pulporadicular treatment of tooth 37. Facial physical examination found an increase in volume in the left genian region, and intraoral observation detected expansion of the corticals in the lower posterior arch of the same side. Panoramic radiography and computed axial tomography showed a multilocular radiolucid image resembling soap bubbles which extended from the mandibular body to the left condyle. A sample was taken for biopsy, which confirmed the diagnosis of follicular pattern ameloblastoma. Segmental mandibular surgery was performed by cervical approach with a safety margin and exarticulation. The portion removed was replaced with a customized titanium prosthesis. Post-operative control showed a good evolution.
Conclusions: Surgery was the basic component of the treatment applied. Surgical resection was followed by reconstruction of the defect with a customized titanium prosthesis, a procedure of great novelty in our environment useful to restore function and esthetic appearance.
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References
Peña V, Leonel T, Guzmán C, Esquivel C, Rodríguez G, Bustillo RJ. Frecuencia de tumores odontogénicos benignos en la Fundación Hospital de la Misericordia (Bogotá, Colombia). Un estudio retrospectivo a nueve años. Universitas Médica. 2016 [acceso: 03/02/2020]; 57(4):467-79. Disponible en: http://www.redalyc.org/articulo.oa?id=231051147005
Santana Garay JC. Atlas de patología del complejo bucal. 2.ª ed. La Habana: ECIMED; 2010.
Effiom OA, Ogundana OM, Akinshipo AO, Akintoye SO. Ameloblastoma: current etiopathological concepts and management. Oral Dis. 2018 [acceso: 03/02/2020]; 24(3):307-16. Disponible en: https://onlinelibrary.wiley.com/doi/full/10.1111/odi.12646
Milman T, Ying GS, Pan W. Ameloblastoma: 25 Year Experience at a Single Institution. Head Neck Pathol. 2016;10(1):513-8. DOI: 10.1007/s12105-016-0734-5
Rehbein J, Becerra F, Fernández A, Niklander S, Marshall M, Esguep A. Maxillofacial Cancer in Children: Part II Malignant Odontogenic and Salivary Gland Tumors. Int. J. Odontostomat. 2016 [acceso: 17/02/2020]; 10(2): 277-82. Disponible en: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2016000200014&lng=es
EI-Naggar AK, Chan JK, Grandis JR, Takata T, Slootweg PJ. WHO Classification of Head and Neck Tumours. 4th ed. Lyon: IARC; 2017.
Urbano del Valle S, Tovío Martínez E, López Aparicio E. Ameloblastoma multiquístico de crecimiento rápido con reconstrucción parcial. Rev Cub Estomatol. 2018 [acceso: 03/02/2020]; 55(4). Disponible en: http://www.revestomatologia.sld.cu/index.php/est/article/view/1784
Hernández Feria O, Sánchez Acuña JG. Neoplasias odontogénicas benignas. Investigaciones Medicoquirúrgicas. 2020 [acceso: 03/07/2020]; 12(2). Disponible en: http://www.revcimeq.sld.cu/index.php/imq/article/view/641
Soluk-Tekkeşin M, Wright J. The World Health Organization Classification of Odontogenic Lesions: A Summary of the Changes of the 2017 (4th Edition). Turk Patholoji Derg. 2018;34:1-18. DOI: 10.5146/tjpath.2017.01410
Speight PM, Takata T. New tumour entities in the 4th edition of the World Health Organization Classification of Head and Neck tumours: odontogenic and maxillofacial bone tumours. Virchows Arch. 2018;472(3):331-9. DOI: 10.1007/s00428-017-2182-3
Abe M, Zong L, Abe T, Takeshima H, Ji J, Ushijima T, Hoshi K. BRAF inhibitor: a novel therapy for ameloblastoma in mandible. Chin J Cancer Res. 2018;30(6):677-8. DOI: 10.21147/j.issn.1000-9604.2018.06.12
Kennedy WR, Werning JW, Kaye FJ, Mendenhall WM. Treatment of ameloblastoma and ameloblastic carcinoma with radiotherapy. Eur Arch Otorhinolaryngol. 2016;273(10):3293-7. DOI: 10.1007/s00405-016-3899-3
Chehal A, Lobo R, Naim A, Azinovic I. Améloblastome du sinus maxillaire traité par radiothérapie. Pan Afr Med J. 2017;26:169. PMCID: PMC5483349
Laborde A, Nicot R, Wojcik T, Ferri J, Raoul G. Ameloblastoma of the jaws: Management and recurrence rate. Eur Ann Otorhinolaryngol Head Neck Dis. 2017 [acceso: 03/02/2020]; 134(1). Disponible en: http://www.sciencedirect.com/science/article/pii/S1879729616301624
Adeel M, Rajput MS, Arain AA, Baloch M, Khan M. Ameloblastoma: Management and Outcome. Cureus. 2018;10(10). PMCID: PMC6289562
López-Núñez CG, Guerrero-Espinosa D, del Bosque-Méndez J, García Rodríguez F. Revisión de los métodos de reconstrucción usados más comúnmente de defectos quirúrgicos en el área de cabeza y cuello en el Hospital Juárez de México. An Orl Mex. 2016 [acceso: 03/02/2020]; 61(1):70-6. Disponible en: http://www.medigraphic.com/cgi-bin/new/resumen.cgi?IDARTICULO=64835
Largo RD, Garvey PB. Updates in Head and Neck Reconstruction. Plast and Reconst Surg. 2017;141(2):271-85. DOI: 10.1097/prs.0000000000004070
Araya I, Canto L, Zamorano G, Yanine N, Domancic S, Villanueva J. Reconstrucción de defectos mandibulares: bloque acrílico como mantenedor de contorno de tejidos. Rev Clin Periodoncia Implantol Rehabil Oral. 2019 [acceso: 27/02/2020]; 12(1):47-4. Disponible en: https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0719-01072019000100047&lng=es
Dupret-Bories A, Vergez S, Meresse T, Brouillet F, Bertrand G. Contribution of 3D printing to mandibular reconstruction after cancer. Eur Ann Otorhinolaryngol Head Neck Dis. 2018;135:133-6. DOI: https://doi.org/10.1016/j.anorl.2017.09.007
Dagnino B, Cifuentes I, Salisbury C. Reconstrucción de cabeza y cuello. Rev. Med Clin Condes. 2016 [acceso: 03/02/2020]; 27(1):29-37. Disponible en: https://www.elsevier.es/es-revista-revista-medica-clinica-las-condes-202-articulo-reconstruccion-de-cabeza-y-cuello-S0716864016000067
Davudov MM, Harirchi I, Arabkheradmand A, Garajei A, Mahmudzadeh H, Shirkhoda M, et al. Evaluation of quality of life in patients with oral cancer after mandibular resection. Medicine. 2019;98(41). DOI: 10.1097/MD.0000000000017431
de Souza NT, Cavalcante RC, de Albuquerque MA. An unusual osteoma in the mandibular condyle and the successful replacement of the temporomandibular joint with a custom-made prosthesis: a case report. BMC Res Notes. 2017;10(1):727. DOI: 10.1186/s13104-017-3060-4
Navarro I, Brenes A, Carr D. Rehabilitación oral maxilar y mandibular con prótesis híbridas, utilizando implantes convencionales de una y dos fases e implantes zigomáticos en paciente con displasia ectodérmica. Caso clínico. Odontología Vital. 2018 [acceso: 03/02/2020]; 29:77-83. Disponible en: https://www.scielo.sa.cr/scielo.php?sript=sci_arttext&pid=S1659-07752018000200077
Sistos Ramírez JE, Jiménez Castillo R, Benavides Ríos A. Manejo protésico quirúrgico del paciente hemimandibulectomizado. Rev Odont Mex. 2013 [acceso: acceso: 03/02/2020]; 17(1):42-6. Disponible en: http://www.scielo.org.mx/scielo.php?sript=sci_arttext&pid=S1870-199X2013000100007&Ing=es
Linsen SS, Oikonomou A, Martini M. Mandibular kinematics and maximum voluntary bite force following segmental resection of the mandible without or with reconstruction. Clin Oral Invest. 2018;22:1707-16. DOI: 10.1007/s00784-017-2263-3
Yang R, Liu Z, Gokavarapu S, Peng C, Cao W, Ji T. Recurrence and cancerization of ameloblastoma: multivariate analysis of 87 recurrent craniofacial ameloblastoma to assess risk factors associated with early recurrence and secondary ameloblastic carcinoma. Chin J Cancer Res. 2017 [acceso: 03/02/2020]; 29(3):189-95. Disponible en: http://www.cjcrcn.org/article/html_9727.html
Carreón-Burciaga RG, González R, Molina-Frechero N, Bologna-Molina R. Immunoexpression of Ki-67, MCM2, and MCM3 in Ameloblastoma and Ameloblastic Carcinoma and Their Correlations with Clinical and Histopathological Patterns. Dis Markers. 2015;10(1):1-8. PMCID: PMC4707386
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