Histopathological characterization in the leukoplakia buccalis in Havana during 10 years
Keywords:
epithelial dysplasia, leukoplakia buccalis.Abstract
The epithelial dysplasia is considered the stronger predictor of a future malignanttransformation of the leukoplakia buccalis. The aim of present paper was to
determine the presence and severity of this type of dysplasia and its association
with the histological alterations of epithelial and connective tissues of mucosa in the
leukoplakia buccalis. A cross-sectional and descriptive research was conducted in
83 biopsies processed by technique of paraffin inclusion and stained with
Hematoxylin and Eosin of patients diagnosed with this entity between 1991-2001
from the Stomatology Faculty of the Medical Sciences University of La Habana. The
92.8 % of patients with a clinical diagnosis of leukoplakia buccalis had slight
epithelial dysplasia, from these and according to its grade of severity, there was
found a slight epithelial dysplasia in the 53.0 %, moderate epithelial dysplasia in
the 36.4 % and a severe epithelial dysplasia in 10.4 %. The parakeratosis was
manifested in the 43.9 % associated with a slight epithelial dysplasia, 78.6 % with
a moderate dysplasia and in the 100 % with the severe one. The epithelial
dysplasia was present in the 57.1 % of cases and the inflammatory infiltrate in the
79.2 % of study samples. Authors conclude that in the study sample of leukoplakia
buccalis there is a high percentage of epithelial dysplasia with predominance of its
slight degree and a association between its severity degree with the different
patterns of keratinization and the intensity of inflammatory infiltrate, something
important in the analysis of its course in face a determined diagnosis y its
prognosis.
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