Inflammatory parameters in saliva and blood from healthy children and adolescents
Keywords:
IL-1, IL-6, TNF-α, RSTBA, O2 -, saliva, blood.Abstract
At present times, there is interest in the use of saliva as a diagnosis, prediction andprogression alternative of different pathologies in relation to the body fluids. To
correlate the concentrations of IL-1, IL-6, TNF-α, substances reactive to
thiobarbituric acid (RSTBA) and O2
-
in the saliva and blood of systematically healthy
children and adolescents. A cross-sectional study was performed in 23 healthy
children and adolescents aged from 4 to 17 underwent to clinical tests to
demonstrate the oral conditions and immunological to identify the cytokine levels
and the RSTBAs by colorimetry trial. There was a significant difference in saliva
samples compared to that of peripheral blood in study cytokines and RSTBAs: IL-1
(blood: 1.646 ± 0.13 pg/mL, saliva: 552.36 ± 75.7 pg/mL; IL-6 (blood: 3.506 ±
1.85 pg/mL, saliva: 26.89 ± 9.97 pg/mL: TNF-α (blood: 12.91 ± 3.05 pg/mL,
saliva: 43.56 ± 6.44 pg/mL), RSTBA (blood: 9.46 ± 3.26 nmol/mL, saliva: 1.26 ±
0.03 nmol/mL). There was not a statistically significant difference among blood and
saliva samples for IL-1, IL-6 and RSTBA values. As regards TNF-α it was
demonstrated a significant correlation, rs= 0.78. There was not evidence of cells
positive to O2 in study samples. Results of correlation analysis obtained among the
saliva and serum samples not offer evidences that saliva may be used as body fluid
allows substituting the serum determination of IL-1, IL-6 and RSTBA. In the case of
the TNF-α, there was a significant correlation, which could to propose the possible
substitution of serum samples for the salivary ones.
Downloads
Downloads
Published
How to Cite
Issue
Section
License
Authors retain all rights to their works, which they can reproduce and distribute as long as they cite the primary source of publication.
The Rev Cubana Estomatol is subject to the Creative Commons Attribution-Non-Commercial 4.0 International License (CC BY-NC 4.0) and follows the publication model of SciELO Publishing Schema (SciELO PS) for publication in XML format.
You are free to:
- Share — copy and redistribute the material in any medium or format.
- Adapt — remix, transform, and build upon the material.
The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- NonCommercial — You may not use the material for commercial purposes.
No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices:
- You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation.
- No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.
Download PDF
