Big multiform erythema triggered by antimicrobials
Keywords:
Stevens-Johnson syndrome, multiform erythema, autoimmune diseasesAbstract
The multiform erythema appears as a systemic disease where skin and the mucousmembranes have participation in relation to some factors such as bacterial or viral
infections and in particular the drugs administration, analgesics and antibiotics in
general. The aim of present paper was the presentation of case of big multiform
erythema triggering by antimicrobials. Authors present the case of a male patient
aged 29 with appearance of ulcerous bullous-vesicular lesions in lips, gums, tongue
and genital mucosa under treatment with 400 mg norfloxacin due to urinary tract
infection for a week. We made support treatment using mouthwashes for oral
hygiene and corticoids ointment for ulcer protection, antihistaminics and nutritional
guiding of a hypercaloric and hyperprotein liquid diet. This syndrome is
characterized as an acute bullous eruptive process involving the patient's quality of
life and there are not specific laboratory tests thus its diagnosis must to be based
on a highly detailed review of anamnesis and the clinical findings.
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