The periodontal disease as a risk for systemic diseases
Keywords:
Periodontal disease, risk, systemic diseasesAbstract
An exhaustive bibliographic review of the presence of the periodontal disease as a risk factorassociated with diverse systemic diseases was made. Some authors have proposed the
emergence of periodontal medicine as a new discipline to explain these associations. The
evidences that appeared in the last decade shed light on the opposite side of the relation
between general health and oral health, that is, the potential effects of the periodontal diseases
on a wide range of organ systems. In the last years, several reports have been based on
epidemiological studies in which the oro-dental diseases are associated with systemic diseases,
such as cerebrovascular and respiratory disorders, diabetes mellitus and adverse results of
pregnancy, due to the lipopolysaccharids and the gram-negative viable bacteria in the biofilm
and proinflammatory cytokines that may enter the blood stream and influence on general
health and on the susceptibility to certain diseases. The proposed models of interaction and
mechanisms, as well as some evidences supporting the stated theories, are collected, giving
special emphasis to the causality between both processes.
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