Treatment of hairy leukoplakia with podophyllum resin at 25 %. Review and presentation of a clinical case

Authors

  • Irene Tamí-Maury Universidad Central de Venezuela. Facultad de Odontología. Universidad Santa María. Caracas.
  • Luis Martínez Universidad Santa María. Caracas.
  • Sally Laforest Universidad Santa María. Caracas
  • Marianna Iovino Universidad Santa María. Caracas

Keywords:

Hairy leukoplakia, HIV, AIDS, podophyllum resin

Abstract

Hairy leukoplakia (VL) is a buccal marker of HIV infection. LV is an asymptomatic lesion that occurs mainly on the lateral edges of the tongue. For aesthetic reasons, particularly when the lesions are very extensive, some patients request treatment. Podophyllin resin (RP) is a topical chemotherapeutic agent widely used by dermatologists to treat human papillomavirus (HPV) infections. We present the clinical case of a 32-year-old homosexual HIV + male, who was treated for presenting bilateral LV in the tongue. RP was applied at 25% in the lesions. After 2 weeks of treatment, a significant involution of the LV was observed. The patient reported minimal side effects that included a burning sensation and pain. No systemic side effects were reported. These preliminary findings suggest that 25% RP may be a relatively safe and cost-effective treatment for VL in seropositive patients.

Downloads

Downloads

Published

2005-10-07

How to Cite

1.
Tamí-Maury I, Martínez L, Laforest S, Iovino M. Treatment of hairy leukoplakia with podophyllum resin at 25 %. Review and presentation of a clinical case. Rev Cubana Estomatol [Internet]. 2005 Oct. 7 [cited 2025 Jun. 20];42(3):61-7. Available from: https://revestomatologia.sld.cu/index.php/est/article/view/2467

Issue

Vol. 42 No. 3 (2005): SEP- DEC

Section

Case Report

License

Authors retain all rights to their works, which they can reproduce and distribute as long as they cite the primary source of publication.

The Rev Cubana Estomatol is subject to the Creative Commons Attribution-Non-Commercial 4.0 International License (CC BY-NC 4.0) and follows the publication model of SciELO Publishing Schema (SciELO PS) for publication in XML format.

You are free to:

  • Share — copy and redistribute the material in any medium or format.
  • Adapt — remix, transform, and build upon the material.

The licensor cannot revoke these freedoms as long as you follow the license terms.

Under the following terms:

No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.

Notices:

  • You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation.
  • No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.