Biological plausibility of the relationship between chronic periodontitis and ischemic stroke

Authors

  • María Elena González Díaz Facultad de Estomatología" Raúl González Sánchez"

Keywords:

periodontal disease, periodontitis, cerebrovascular disease, cerebral infarction.

Abstract

Introduction: True periodontal pockets are an important reservoir of gram-negative bacteria which may exert an influence on distant sites in a variety of manners, bringing about systemic alterations such as diseases derived from atherosclerosis.
Objective: Explain the theoretical foundations supporting the proposal of chronic periodontitis as a risk factor for ischemic stroke.
Content: 1) Atherosclerosis and cerebrovascular disease, an overview of their pathogenesis. 2) The periodontal microbiota, bases for its association with atherosclerosis and ischemic stroke.
Topic presentation: Inflammation is an element of vital importance in all the stages of the atherosclerotic process, be it its onset, progress or complications. By their nature, chronic immunoinflammatory periodontal diseases and the associated anaerobic subgingival infection, constitute a metastatic injury that produces and spreads inflammatory mediators leading to atherosclerosis and participating in the colonization and rupture of atheromatous plaques, which are processes involved in the pathogenesis of ischemic stroke.
Final considerations: Better knowledge about the risk relationship between chronic periodontitis and ischemic stroke would allow a rational use of strategies for the prevention and treatment of cerebrovascular disease based on detection of inflammatory processes such as chronic periodontal conditions.

Downloads

Download data is not yet available.

Author Biography

María Elena González Díaz, Facultad de Estomatología" Raúl González Sánchez"

Docente del departamento de Periodoncia de la facultad de Estomatología.Especialista de II grado en Periodoncia. Master en Educación Médica. Profesora Auxiliar

Downloads

Published

2019-02-22

How to Cite

1.
González Díaz ME. Biological plausibility of the relationship between chronic periodontitis and ischemic stroke. Rev Cubana Estomatol [Internet]. 2019 Feb. 22 [cited 2025 Mar. 12];56(1):93-102. Available from: https://revestomatologia.sld.cu/index.php/est/article/view/1816

Issue

Vol. 56 No. 1 (2019): JAN- MAR

Section

Master Conference

License

Authors retain all rights to their works, which they can reproduce and distribute as long as they cite the primary source of publication.

The Rev Cubana Estomatol is subject to the Creative Commons Attribution-Non-Commercial 4.0 International License (CC BY-NC 4.0) and follows the publication model of SciELO Publishing Schema (SciELO PS) for publication in XML format.

You are free to:

  • Share — copy and redistribute the material in any medium or format.
  • Adapt — remix, transform, and build upon the material.

The licensor cannot revoke these freedoms as long as you follow the license terms.

Under the following terms:

No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.

Notices:

  • You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation.
  • No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.