Antimicrobial effect of cinnamaldehyde, thymol, eugenol and chitosan on Streptococcus mutans strains
Keywords:
S. mutans, thymol, cinnamaldehyde, eugenol, chitosan, caries.Abstract
Objective: to evaluate the antimicrobial activity of cinnamaldehyde, thymol, eugenol and chitosan compared to chlorhexidine-0.12 % on Streptococcus mutans strains.
Methods: bacterial susceptibility tests were performed on S. mutans strains with disks embedded in eugenol, cinnamaldehyde, chitosan and thymol, at 0.1 % and 1 % with a positive control of 0.12 % chlorhexidine, evaluating existing inhibition zones after 24 and 48 hours.
Results: cinnamaldehyde-1 % showed the best control power over the growth of S. mutans, presenting 19.91 mm and 24.44 mm of inhibition halos after 24 and 48 hours, respectively, with a significant difference of p< 0.05 between the two intervals. When the cinnamaldehyde-1 % was compared with the positive control of chlorhexidine-0.12 %, no significant differences were found (p> 0.05).
Conclusions: cinnamaldehyde-1 % had the best results followed by chitosan, eugenol and thymol in the same concentration compared to chlorhexidine-0.12 % after both 24 and 48 hours.
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