Publique un comentario 
Descargar PDF
Prevalencia de carcinoma intraóseo primario derivado de quiste dentígero
Resumen
Introducción: La malignización de quiste dentígero a carcinoma intraóseo primario es infrecuente, poco documentada en la literatura. Corresponde del el 1 % al 2,5 % del total de tumores odontogénicos y es exclusiva de los huesos maxilares. Más común en hombres sobre 50 años de edad. Las características clínicas se asocian a edema, movilidad de piezas dentarias, parestesia, y la mayoría ocurre en ausencia de dolor, características que hacen difícil su diagnóstico y presentan un desafío para los patólogos.
Objetivo: Revisar la prevalencia de carcinoma intraóseo primario derivados de quiste dentígero en los últimos 15 años publicados en PubMed
Métodos: Se realizó una revisión de la literatura en un periodo que considera los últimos 15 años. Se consultó la base de datos PubMed utilizando los términos: “dentigerous cyst prevalence”, “primary intraosseous squamous cell carcinoma”, “dentigerous primary intraosseous squamous cell carcinoma”. Se incluyeron artículos en inglés y español. De los 217 artículos, se suscribió a 39 para hacer el cruce de datos.
Análisis e integración de los resultados: Para reconocer una enfermedad tan agresiva como el carcinoma intraóseo primario derivado de quiste dentígero hay que estudiar sus características clínicas, radiográficas y sintomatología. Su íntima relación con el quiste dentígero, el cual es el más prevalente de los quistes del desarrollo hace fundamental el profundo conocimiento de ambos. El carcinoma intraóseo primario se presenta como un desafío para los clínicos por su baja sintomatología y pobre sobrevida, con un total de 44 823 quistes odontogénicos estudiados, 9806 se diagnosticaron como quistes dentígeros, y 22 se malignizaron a carcinoma intraóseo primario, para un 0,32 % del total.
Conclusiones: La malignización de quiste dentígero a carcinoma intraóseo primario tiene una baja incidencia, pero se presenta silente haciendo difícil su diagnóstico precoz. Se recomienda biopsia de protocolo para cada caso de quiste dentígero y así evitar la baja sobrevida que produce el carcinoma intraóseo primario.Palabras clave
Referencias
Morgan P. Odontogenic tumors: a review. Periodontology. 2000. 2011;57(1):160-76.
Soluk-Tekkesin M, Wright JM, The World Health Organization Classification of Odontogenic Lesions: A Summary of the Changes of the 2017. Turk Patoloji Derg. 2018;31(1).
Borrás-Ferres J, Sánchez-Torres A, Gay-Escoda C. Malignant changes developing from odontogenic cysts: A systematic review. J Clin Exp Dent. 2016;1;8(5):e622-e628.
Wenguang X, Hao S, Xiaofeng Q, Zhiyong W, Yufeng W, Qingang H, et al. Prognostic Factors of Primary Intraosseous Squamous Cell Carcinoma (PIOSCC): A Retrospective Review. PLoS ONE. 2016;11(4):e0153646.
Pardhe N, Bhagalia S, Nayak PA, Sireesha SK. Primary intraosseous squamous cell carcinoma: a devil in disguise. BMJ Case Rep. 2013;2013:bcr2013009639.
Ochsenius G, Escobar E, Godoy L, Peñafiel C. Odontogenic cysts: analysis of 2,944 cases in Chile. Med Oral Patol Oral Cir Bucal. 2007 Mar 1;12(2):E85-91.
Jones AV, Craig GT, Franklin CD. Range and demographics of odontogenic cysts diagnosed in a UK population over a 30-year period. J Oral Pathol Med. 2006 Sep;35(8):500-7.
Johnson NR, Gannon OM, Savage NW, Batstone MD. Frequency of odontogenic cysts and tumors: a systematic review. J Investig Clin Dent. 2014 Feb;5(1):9-14.
Mohajerani H, Esmaeelinejad M, Sabour S, Aghdashi F, Dehghani N. Diagnostic Factors of Odontogenic Cysts in Iranian Population: A Retrospective Study Over the Past Two Decades. Iran Red Crescent Med J. 2015 Jun 30;17(6):e21793.
Villasis-Sarmiento L, Portilla-Robertson J, Melendez-Ocampo A, Gaitan-Cepeda LA, Leyva-Huerta ER. Prevalence and distribution of odontogenic cysts in a Mexican sample. A 753 cases study. J Clin Exp Dent. 2017 Apr 1;9(4):e531-e538.
Fomete B, Osunde OD, Ogbeifun J, Agbara R, Ononiwu CN. A 10-Year Retrospective Analysis of 64 Cases of Cystic Lesions of the Oral and Maxillofacial Region in a Nigerian Tertiary Hospital. Oman Med J. 2016 Nov;31(6):434-8.
Kambalimath DH, Kambalimath HV, Agrawal SM, Singh M, Jain N, Anurag B, et al. Prevalence and distribution of odontogenic cyst in Indian population: a 10 year retrospective study. J Maxillofac Oral Surg. 2014 Mar;13(1):10-5.
Ha WN, Kelloway E, Dost F, Farah CS. A retrospective analysis of oral and maxillofacial pathology in an Australian paediatric population. Aust Dent J. 2014 Jun;59(2):221-5.
Del Corso G, Righi A, Bombardi M, Rossi B, Dallera V, Pelliccioni GA, et al. Jaw cysts diagnosed in an Italian population over a 20-year period. Int J Surg Pathol. 2014 Dec;22(8):699-706.
Bilodeau EA, Collins BM. Odontogenic Cysts and Neoplasms. Surg Pathol Clin. 2017 Mar;10(1):177-222.
Demirkol M, Ege B, Yanik S, Aras MH, Ay S. Clinicopathological study of jaw cysts in southeast region of Turkey. Eur J Dent. 2014 Jan;8(1):107-11.
Patil S, Halgatti V, Khandelwal S, Santosh BS, Maheshwari S. Prevalence of cysts and tumors around the retained and unerupted third molars in the Indian population.
J Oral Biol Craniofac Res. 2014 May-Aug;4(2):82-7.
Rioux-Forker D, Deziel AC, Williams LS, Muzaffar AR. Odontogenic Cysts and Tumors. Ann Plast Surg. 2019 Apr;82(4):469-77.
de Souza LB, Gordón-Núñez MA, Nonaka CF, de Medeiros MC, Torres TF, Emiliano GB. Odontogenic cysts: demographic profile in a Brazilian population over a 38-year period. Med Oral Patol Oral Cir Bucal. 2010 Jul 1;15(4):e583-90.
Selvamani M, Donoghue M, Basandi PS. Analysis of 153 cases of odontogenic cysts in a South Indian sample population: a retrospective study over a decade. Braz Oral Res. 2012 Jul-Aug;26(4):330-4.
Tekkesin MS, Olgac V, Aksakalli N, Alatli C. Odontogenic and nonodontogenic cysts in Istanbul: analysis of 5088 cases. Head Neck. 2012 Jun;34(6):852-5.
Zhang LL, Yang R, Zhang L, Li W, MacDonald-Jankowski D, Poh CF. Dentigerous cyst: a retrospective clinicopathological analysis of 2082 dentigerous cysts in British Columbia, Canada. Int J Oral Maxillofac Surg. 2010 Sep;39(9):878-82.
Terauchi M, Akiya S, Kumagai J, Ohyama Y, Yamaguchi S. An Analysis of Dentigerous Cysts Developed around a Mandibular Third Molar by Panoramic Radiographs. Dent J (Basel). 2019 Feb 4;7(1).
Li N, Gao X, Xu Z, Chen Z, Zhu L, Wang J, et al. Prevalence of developmental odontogenic cysts in children and adolescents with emphasis on dentigerous cyst and odontogenic keratocyst (keratocystic odontogenic tumor). Acta Odontol Scand. 2014 Nov;72(8):795-800.
Buchbender M, Neukam FW, Lutz R, Schmitt CM. Treatment of enucleated odontogenic jaw cysts: a systematic review. Oral Surg Oral Med Oral Pathol Oral Radiol. 2018 May;125(5):399-406.
Geetha P, Avinash Tejasvi ML, Babu BB, Bhayya H, Pavani D. Primary intraosseous carcinoma of the mandible: A clinicoradiographic view. J Cancer Res Ther. 2015 Jul-Sep;11(3):651.
Lukandu OM, Micha CS. Primary intraosseous squamous cell carcinoma arising from keratocystic odontogenic tumor. Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 Nov;120(5):e204-9.
Naruse T, Yanamoto S, Sakamoto Y, Ikeda T, Yamada SI, Umeda M. Clinicopathological Study of Primary Intraosseous Squamous Cell Carcinoma of the Jaw and a Review of the Literature. J Oral Maxillofac Surg. 2016 Dec;74(12):2420-7.
Martínez-Martínez M, Mosqueda-Taylor A, Delgado-Azañero W, Rumayor-Piña A, de Almeida OP. Primary intraosseous squamous cell carcinoma arising in an odontogenic keratocyst previously treated with marsupialization: case report and immunohistochemical study. Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Apr;121(4):e87-95.
Huang JW, Luo HY, Li Q, Li TJ. Primary intraosseous squamous cell carcinoma of the jaws. Clinicopathologic presentation and prognostic factors. Arch Pathol Lab Med. 2009 Nov;133(11):1834-40.
Boni P, Sozzi D, Novelli G, Pagni F, Valente G, Bozzetti A. Primary Intraosseous Squamous Cell Carcinoma of the Jaws: 6 New Cases, Experience, and Literature Comparison. J Oral Maxillofac Surg. 2016 Mar;74(3):541-6.
Bodner L, Manor E, Shear M, van der Waal I. Primary intraosseous squamous cell carcinoma arising in an odontogenic cyst: a clinicopathologic analysis of 116 reported cases. J Oral Pathol Med. 2011 Nov;40(10):733-8.
Woolgar JA, Triantafyllou A, Ferlito A, Devaney KO, Lewis JS Jr, Reinaldo A, et al. Intraosseous carcinoma of the jaws: a clinicopathologic review. Part III: Primary intraosseous squamous cell carcinoma. Head Neck. 2013 Jun;35(6):906-9.
Medawela RMSHB, Jayasuriya NSS, Ratnayake DRDL, Attygalla AM, Siriwardena BSMS. Squamous cell carcinoma arising from a keratocystic odontogenic tumor: a case report. J Med Case Rep. 2017 Dec 1;11(1):335.
Grisar K, Schol M, Hauben E, Schoenaers J, Politis C. Primary intraosseous squamous cell carcinoma of the mandible arising from an infected odontogenic cyst: A case report and review of the literature. Oncol Lett. 2016 Dec;12(6):5327-31.
Spinelli G, Arcuri F, Rocchetta D, Agostini T. Primary intraosseous squamous cell carcinoma of the mandible. Is adjuvant therapy still necessary to improve a 5-year survival rate? J Craniofac Surg. 2014 May;25(3):1137-9.
Alotaibi O, Al-Zaher N, Alotaibi F, Khoja H, Qannam A. Solid-type primary intraosseous squamous-cell carcinoma in the mandible: Report of a rare case. Hematol Oncol Stem Cell Ther. 2016 Sep;9(3):118-22.
Panneerselvam K, Parameswaran A, Kavitha B, Panneerselvam E. Primary intraosseous squamous cell carcinoma in a dentigerous cyst. South Asian J Cancer. 2017;6:105-17.
Gay-Escoda C, Camps-Font O, López-Ramírez M, Vidal-Bel A. Primary intraosseous squamous cell carcinoma arising in dentigerous cyst: Report of 2 cases and review of the literature. J Clin Exp Dent. 2015 Dec 1;7(5):e665-70.
